Ibuprofen page launched — PK data, structure viewer, and dose curve
DrugTheGuide's first drug page covers ibuprofen (racemate, dexibuprofen, lysine and sodium salt variants) with pharmacokinetic tiles sourced from FDA product labels and PubChem, an interactive one-compartment dose-curve simulator, a ball-and-stick structure viewer, and the variants comparison table.
What launched
DrugTheGuide's first drug page covers ibuprofen — a widely used NSAID in the propionic acid class (ATC M01AE01 ↗) with a CAS number of 15687-27-1. The page covers four variants: the racemate, dexibuprofen ↗, ibuprofen lysine, and ibuprofen sodium.
Data sources on the page
Pharmacokinetic values (bioavailability F=0.9, Vd≈10 L, t½≈2 h, protein binding >99%) are sourced from FDA-approved product labels on DailyMed ↗ and PubChem CID 3672 ↗. Molecular coordinates used in the structure viewer are derived from the PubChem 3D conformer ↗. Drug class and ATC data are from RxNav (NLM) ↗.
Interactive features
The page includes: (1) a one-compartment oral absorption dose-curve simulator that models C(t) = (F·D·ka)/(V·(ka−ke))·(e−ke·t − e−ka·t) with adjustable dose, repeat dosing, and interval; (2) a ball-and-stick structure viewer rotating in the browser using pure CSS divs — no WebGL; (3) a mass-to-moles calculator tied to the selected variant's molar mass. See the half-life glossary entry for background on the PK model used.
FAQ
How often is DrugTheGuide updated?
DrugTheGuide is a static site rebuilt on a scheduled basis when source data (FDA labels, PubChem, RxNorm) changes. Major FDA safety events trigger priority rebuilds. The News page logs all site updates. Data freshness indicators appear on each drug page value, showing how recently each data point was verified against its source.